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奶牛群中伪结核棒状杆菌疫情的群体水平分析。

A herd level analysis of a Corynebacterium pseudotuberculosis outbreak in a dairy cattle herd.

作者信息

Yeruham Israel, Friedman Samuel, Perl Samuel, Elad Daniel, Berkovich Yair, Kalgard Yoram

机构信息

'Hachaklait' Gedera and the Koret School of Veterinary Medicine, the Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel.

出版信息

Vet Dermatol. 2004 Oct;15(5):315-20. doi: 10.1111/j.1365-3164.2004.00388.x.

DOI:10.1111/j.1365-3164.2004.00388.x
PMID:15500484
Abstract

Corynebacterium pseudotuberculosis infection in an Israeli dairy cattle herd is described. The disease was characterized by ulcerative granulomatous lesions, which occurred in an epidemic form. Thirty-two cows and two heifers were affected, the ratio of the number affected to number at risk being 17.5 : 1 and 9.5 : 1, respectively. The culling rate was 50% of the affected animals. Most of the affected animals were cows (91.2%), with one first-calving cow (2.9%) and two heifers (5.9%) also affected. The infection occurred during the summer to autumn months (August-December), and lasted 118 days. The incubation period is about 2 months. The disease appeared in two clinical forms - cutaneous and mastitic - or as a mixed form. C. pseudotuberculosis organisms that were isolated from the ulcerative granulomatous lesions and from milk samples failed to reduce nitrate. A decrease in milk production (4%) and an increase in the bulk-milk somatic cell count from a herd mean of 240 x 10(3) mL(-1) to 460 x 10(3) mL(-1) were noted during the morbidity period. The organism was isolated from milk samples of eight animals (25%). Clinical, epizootiological and microbiological aspects of the infection are described.

摘要

本文描述了以色列一个奶牛群中发生的伪结核棒状杆菌感染情况。该病的特征为溃疡性肉芽肿病变,呈流行形式出现。32头奶牛和2头小母牛受到感染,受影响数量与危险数量之比分别为17.5:1和9.5:1。受影响动物的淘汰率为50%。大多数受影响动物为奶牛(91.2%),1头初产奶牛(2.9%)和2头小母牛(5.9%)也受到感染。感染发生在夏季至秋季(8月至12月)期间,持续了118天。潜伏期约为2个月。该病表现为两种临床形式——皮肤型和乳房型——或混合型。从溃疡性肉芽肿病变和牛奶样本中分离出的伪结核棒状杆菌不能还原硝酸盐。发病期间,牛奶产量下降了4%,全群牛奶体细胞计数从平均240×10³/mL升至460×10³/mL。从8头动物(25%)的牛奶样本中分离出了该病原体。本文描述了该感染的临床、流行病学和微生物学方面的情况。

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