Shpigel N Y, Elad D, Yeruham I, Winkler M, Saran A
Ambulatory Clinic, Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel.
Vet Rec. 1993 Jul 24;133(4):89-94. doi: 10.1136/vr.133.4.89.
An outbreak of Corynebacterium pseudotuberculosis infection in an Israeli dairy herd appeared in four clinical forms: cutaneous, mastitic, visceral and a mixed form. Only cows were affected and susceptibility increased with age. Most cases occurred during a short period in the summer months. The total morbidity rate was 13.7 per cent involving 41 cows. Thirty cows were affected by the cutaneous form, five by the mastitic form, four by the mastitic and cutaneous forms, one by the mastitic and visceral forms and one by the visceral form. The cutaneous form appeared as one or two pyogranulomatous lesions affecting the body or head. Subclinical to severe clinical mastitis was found in the mastitic form. In the visceral form the upper and lower respiratory system were affected by multiple purulent lymphadenitis. All the cutaneous lesions recovered irrespective of treatment. Mastitis did not respond to treatment and severely affected milk production in most cases. All the isolates of C pseudotuberculosis were nitrate reductase negative. Most isolates were sensitive to norfloxacin, cephalothin, methicillin, kanamycin and furazolidone and resistant to ampicillin, lincomycin and neomycin.
以色列一个奶牛场爆发了伪结核棒状杆菌感染，出现了四种临床症状：皮肤型、乳房炎型、内脏型和混合型。仅奶牛受到感染，易感性随年龄增长而增加。大多数病例发生在夏季的短时间内。总发病率为13.7%，涉及41头奶牛。30头奶牛出现皮肤型症状，5头出现乳房炎型症状，4头出现乳房炎和皮肤混合型症状，1头出现乳房炎和内脏混合型症状，1头出现内脏型症状。皮肤型表现为一两个影响身体或头部的脓性肉芽肿病变。乳房炎型症状从亚临床到严重临床乳腺炎均有发现。内脏型中，上下呼吸系统受到多发性化脓性淋巴结炎的影响。所有皮肤病变无论是否治疗均已痊愈。乳房炎对治疗无反应，且在大多数情况下严重影响产奶量。所有伪结核棒状杆菌分离株的硝酸盐还原酶均为阴性。大多数分离株对诺氟沙星、头孢噻吩、甲氧西林、卡那霉素和呋喃唑酮敏感，对氨苄西林、林可霉素和新霉素耐药。
