Skoet Rikke, Olsen Jorn, Mathiesen Bent, Iversen Lars, Johansen Jeanne Duus, Agner Tove
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Contact Dermatitis. 2004 Oct;51(4):159-66. doi: 10.1111/j.0105-1873.2004.00423.x.
Occupational hand eczema (OHE) is the most frequently recognized work-related disease in Denmark and the annual cost to society is high. Understanding of the epidemiology of OHE is essential to be able to give appropriate recommendations for its prevention. The study comprised 758 persons, 490 females and 268 males with recognized OHE in the period October 2001 to November 2002. Data were obtained prospectively from the National Board of Industrial Industry Registry and from a self-administered questionnaire (response rate, 82%). The most frequently recognized diagnosis was irritant contact dermatitis (ICD), mainly caused by wet occupations. The proportion of occupational ICD was equal for males and females, 59.7% and 63.1%, respectively. The estimated rates of OHE were high for bakers, hairdressers and dental surgery assistants, and a high proportion of apprentices were found among hairdressers. The prevalence of atopic dermatitis was low (16.4%) compared to previous studies among hand eczema patients. The prevalence of occupational allergic contact dermatitis in the study population was substantially higher among males than females, and the most frequent causes among males were allergy to chromium (leather exposure), rubber additives (gloves) and nickel due to exposure from work tools and metalworking industry.
职业性手部湿疹(OHE)是丹麦最常被确诊的与工作相关的疾病,给社会带来的年度成本很高。了解OHE的流行病学对于能够给出适当的预防建议至关重要。该研究涵盖了758人,其中490名女性和268名男性在2001年10月至2002年11月期间被确诊患有OHE。数据是前瞻性地从国家工业登记局和一份自行填写的问卷中获得的(回复率为82%)。最常被确诊的诊断是刺激性接触性皮炎(ICD),主要由潮湿的工作引起。职业性ICD在男性和女性中的比例相当,分别为59.7%和63.1%。面包师、美发师和牙科手术助理的OHE估计发病率很高,且在美发师中发现有很大比例的学徒。与之前对手部湿疹患者的研究相比,特应性皮炎的患病率较低(16.4%)。研究人群中职业性过敏性接触性皮炎的患病率在男性中显著高于女性,男性中最常见的病因是对铬(皮革接触)、橡胶添加剂(手套)以及因工作工具和金属加工行业接触而导致的镍过敏。