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射频热消融术和椎体成形术治疗肿瘤性椎体骨折

Radiofrequency Heat Ablation and Vertebroplasty in the treatment of neoplastic vertebral body fractures.

作者信息

Masala Salvatore, Roselli Mario, Massari Francesco, Fiori Roberto, Ursone Antonio, Fossile Emanuela, Laudisi Anastasia, Simonetti Giovanni

机构信息

Departments of Interventional Radiology, University of Rome, Tor Vergata, Rome, Italy.

出版信息

Anticancer Res. 2004 Sep-Oct;24(5B):3129-33.

Abstract

BACKGROUND

Metastatic cancer is the most common malignant disease of the skeletal system. Traditionally, conventional fractionated external beam radiotherapy has been the treatment of choice. Recently, minimally invasive surgical techniques (MISS) have been added to the therapeutic armamentarium. The purpose of our study was to assess the effectiveness and safety of Radiofrequency Heat Ablation and Vertebroplasty in the treatment of neoplastic Vertebral Compressive Fractures (VCF). The aim of radiofrequency heat ablation is to destroy the tumor tissue before stabilizing the vertebra through the intrasomatic injection of cement.

PATIENTS AND METHODS

We treated patients with unremitting pain over spine, in absence of symptomatic spinal cord or roots compression and refractory to conventional therapeutic options such as radiation therapy, chemotherapy, surgery and use of analgesics.

RESULTS

The method demonstrated swift pain relief associated with an evident augmentation in the weight-bearing resistance.

CONCLUSION

The association of Radiofrequency Heat Ablation and Vertebroplasty is an effective, simple and safe treatment of vertebral collapse consequent to metastases.

摘要

背景

转移性癌症是骨骼系统最常见的恶性疾病。传统上,常规分割外照射放疗一直是首选治疗方法。最近,微创外科技术(MISS)已被纳入治疗手段。我们研究的目的是评估射频热消融和椎体成形术治疗肿瘤性椎体压缩骨折(VCF)的有效性和安全性。射频热消融的目的是在通过体内注射骨水泥稳定椎体之前破坏肿瘤组织。

患者和方法

我们治疗了脊柱疼痛持续、无症状性脊髓或神经根受压且对放疗、化疗、手术和使用镇痛药等传统治疗方案无效的患者。

结果

该方法显示出迅速的疼痛缓解,并伴有负重抵抗力明显增强。

结论

射频热消融和椎体成形术联合应用是治疗转移性椎体塌陷的一种有效、简单且安全的方法。

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