胎儿晶状体中的乳酸脱氢酶同工酶。
Lactate dehydrogenase isoenzyme of lens in fetus.
作者信息
Ding Kexi, Zhang Yasong
机构信息
Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
出版信息
Yan Ke Xue Bao. 2002 Sep;18(3):194-6.
PURPOSE
The LDH isoenzyme patterns were evaluated in lens of fetus to study the metabolism in human lenses.
METHODS
LDH isoenzyme electrophoresis was performed in 15 lenses of human fetus aged from 4 - 6 months.
RESULTS
There are 5 bands of LDH in fetus lens. LDH4 lever is the highest, and LDH1 is the lowest, especially in the cortex of lens. LDH1 is higher in lens of 4 months of age than in that of 5 and 6 months of age.
CONCLUSIONS
LDH isoenzyme in lens of fetus shows mainly anaerobic metabolism in development, but there is also aerobic metabolism, especially in younger fetus.
目的
评估胎儿晶状体中的乳酸脱氢酶同工酶谱，以研究人类晶状体的代谢。
方法
对15个4 - 6个月龄的人类胎儿晶状体进行乳酸脱氢酶同工酶电泳。
结果
胎儿晶状体中有5条乳酸脱氢酶带。乳酸脱氢酶4水平最高，乳酸脱氢酶1最低，尤其是在晶状体皮质中。4个月龄胎儿的晶状体中乳酸脱氢酶1高于5个月龄和6个月龄胎儿的晶状体。
结论
胎儿晶状体中的乳酸脱氢酶同工酶在发育过程中主要表现为无氧代谢，但也存在有氧代谢，尤其是在较年幼的胎儿中。
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