Vesell E S
Science. 1965 Dec 24;150(3704):1735-7. doi: 10.1126/science.150.3704.1735.
Human platelets and bovine lens fibers contain lactate dehydrogenase-3 (LDH-3) as the predominant isozyme but only very faint traces of LDH-5. Since the platelets and lens fibers, like mature human erythrocytes, lack a nucleus, the results strengthen the case for a previously developed association between LDH-5 and the cell nucleus. These three cell types are mainly anaerobic, and therefore their isozyme patterns are incompatible with the theory that anaerobic tissues exhibit predominantly LDH-5 and aerobic tissues mainly LDH-1.
人血小板和牛晶状体纤维含有乳酸脱氢酶-3（LDH-3）作为主要同工酶，但仅含有极微量的LDH-5。由于血小板和晶状体纤维，如同成熟的人类红细胞一样，没有细胞核，这些结果支持了先前提出的LDH-5与细胞核之间的关联。这三种细胞类型主要进行无氧代谢，因此它们的同工酶模式与无氧组织主要表现为LDH-5而有氧组织主要表现为LDH-1的理论不相符。
