Burton Matthew, Nyong'o Omondi, Burton Kathryn, John Wilhelmina, Inkoom Ebenezer, Pinder Margaret, Corrah Tumani, Johnson Gordon, Bailey Robin
Medical Research Council Laboratories, Fajara, The Gambia.
Trop Doct. 2004 Oct;34(4):214-8. doi: 10.1177/004947550403400409.
A characteristic retinopathy associated with a poor prognosis has previously been described in African children with established cerebral malaria. However, relatively little is known about retinal abnormalities in children with severe non-cerebral malaria, the group most at risk of developing the cerebral complications of this disease. In this study the prevalence, pattern, clinical significance and accessibility to clinical examination of this characteristic retinopathy are described in 106 Gambian children admitted consecutively to hospital with severe malaria, including six with established cerebral malaria.
先前已描述过患有确诊脑型疟疾的非洲儿童中存在一种与预后不良相关的特征性视网膜病变。然而,对于患有严重非脑型疟疾的儿童(该疾病发生脑部并发症风险最高的群体)的视网膜异常情况,我们所知相对较少。在本研究中,我们描述了106名连续入院治疗严重疟疾的冈比亚儿童中这种特征性视网膜病变的患病率、模式、临床意义以及临床检查的可及性,其中包括6名患有确诊脑型疟疾的儿童。