Borgström P, Schmidt J A, Bruttig S P, Intaglietta M, Arfors K E
La Jolla Institute for Experimental Medicine, California 92037.
Circ Shock. 1992 Jan;36(1):57-61.
Laser Doppler flux (LDF) was used to detect flowmotion (regular cyclic alterations in red blood cell flux) in the left gastrocnemius muscle of 14 rabbits that were bled 30% of their blood volume and let to recover spontaneously for 30 min. Only rabbits that met stated inclusion criteria during control conditions were used in the study. During control conditions when femoral artery pressure averaged 68 mm Hg (range 60-80), no animal displayed regular flowmotion. After the end of the acute hemorrhage, arterial pressure was 35 mm Hg (20-51) and slow wave flowmotion appeared instantaneously in 13 of the 14 animals. The maximum relative amplitude of the induced flowmotion was 31% (7-100) and the frequency was 1.8 cycles per minute (cpm) (1.4-4.0). Flowmotion persisted throughout the 30 min observation period in 11 animals, during which time arterial pressure recovered to 46 mm Hg (42-50). Fast-wave flowmotion was not detected in the present study. These results suggest that slow-wave flowmotion as measured with LDF is not a phenomenon characteristic of normal regulation of blood flow in skeletal muscle. After a 30% fixed-volume hemorrhage, slow-wave flowmotion is induced as arterial pressure drops below a certain threshold.
激光多普勒血流仪（LDF）用于检测14只家兔左腓肠肌的血流运动（红细胞通量的规律性周期性变化），这些家兔放血30%血容量后让其自发恢复30分钟。研究仅使用在对照条件下符合既定纳入标准的家兔。在对照条件下，股动脉平均压为68毫米汞柱（范围60 - 80）时，没有动物表现出规律性血流运动。急性出血结束后，动脉压为35毫米汞柱（20 - 51），14只动物中有13只立即出现慢波血流运动。诱导的血流运动的最大相对幅度为31%（7 - 100），频率为每分钟1.8次循环（cpm）（1.4 - 4.0）。11只动物在整个30分钟观察期内血流运动持续存在，在此期间动脉压恢复到46毫米汞柱（42 - 50）。本研究未检测到快波血流运动。这些结果表明，用LDF测量的慢波血流运动不是骨骼肌血流正常调节的特征现象。在30%固定容量出血后，随着动脉压降至一定阈值以下会诱导出慢波血流运动。
