Brown D, Fletcher H M, Myrie M O, Reid M
Cornwall Regional Hospital, Montego Bay, St. James, Kingston, Jamaica.
J Obstet Gynaecol. 1999 Mar;19(2):139-41. doi: 10.1080/01443619965435.
Sixteen women, with uterine fibroids in pregnancy, who were treated by caesarean myomectomy, were compared retrospectively with 16 women, without uterine fibroids who had caesarean section during the same period. Myomectomy was performed at caesarean section after delivery of the baby and the placenta, with the administration of intravenous oxytocin. The fibroid defects were occluded with continuous interlocking and fixed sutures. Routine caesarean section was performed on the subjects in the control group. The comparative efficacy of the procedure was measured by comparing pre- and post-operative haemoglobin levels, measured blood loss, need for blood transfusion, post-operative febrile morbidity and length of hospital stay in both groups. Caesarean myomectomy resulted in a mean blood loss of 495 ml (range 200-1000 ml) compared with 355 ml (range 150-900 ml) in the control group (P =0.907). The caesarean myomectomy group had a mean fall in haemoglobin level of 1.7 g/dl compared with a fall of 1.4 g/dl in the control group. There were no significant differences between the groups in the need for blood transfusion, post-operative febrile morbidity or length of hospital stay. The results indicate that caesarean myomectomy is safe and offers no significant increased risk to the patient over caesarean section alone. This is beneficial to the health sector by the avoidance of an interval myomectomy hence justifying the cost effectiveness of the procedure.
对16例孕期患有子宫肌瘤且接受剖宫产肌瘤切除术的女性与16例同期进行剖宫产但无子宫肌瘤的女性进行回顾性比较。在胎儿和胎盘娩出后行剖宫产时进行肌瘤切除术,并静脉注射催产素。肌瘤缺损处用连续锁边固定缝线缝合。对照组受试者行常规剖宫产。通过比较两组术前和术后的血红蛋白水平、测量失血量、输血需求、术后发热发病率和住院时间来衡量该手术的比较疗效。剖宫产肌瘤切除术的平均失血量为495毫升(范围200 - 1000毫升),而对照组为355毫升(范围150 - 900毫升)(P = 0.907)。剖宫产肌瘤切除组的血红蛋白水平平均下降1.7克/分升,而对照组下降1.4克/分升。两组在输血需求、术后发热发病率或住院时间方面无显著差异。结果表明,剖宫产肌瘤切除术是安全的,与单纯剖宫产相比,对患者没有显著增加的风险。这通过避免二期肌瘤切除术对卫生部门有益,因此证明了该手术的成本效益。