Keren S, Argaman E, Golan M
Institute of Gastroenterology, Hillel Yaffe Medical Center, Hadera, Israel.
Dig Dis Sci. 1992 Apr;37(4):603-8. doi: 10.1007/BF01307587.
The aim of the study was to investigate whether a soft solid bolus can induce abnormal manometric patterns in patients with dysphagia and normal standard manometry. The study group comprised 12 normal volunteers and 22 patients with dysphagia. Manometry was performed using 10 wet swallows followed by 10 swallows of marshmallow. The results show: (1) in normal subjects the mean contraction amplitude is significantly greater (P less than 0.035) and the velocity of propagation significantly slower (P less than 0.003) for soft solid swallows compared with wet swallows; (2) in normal subjects there are fewer abnormal contractions after soft solid swallows than after wet swallows; (3) in 15 patients, soft solid swallows induced non-peristaltic contractions and/or contractions of extreme amplitude and/or duration that were not observed after wet swallows; (4) in patients, the probability of inducing abnormal contractions after soft solid swallows is significantly greater than after wet swallows (P less than 0.0001). We conclude that soft solid swallowing is useful in the study of patients with dysphagia.
本研究的目的是调查软固体食团是否会在吞咽困难且标准测压正常的患者中诱发异常测压模式。研究组包括12名正常志愿者和22名吞咽困难患者。通过10次湿吞咽，随后10次吞咽棉花糖进行测压。结果显示：（1）在正常受试者中，与湿吞咽相比，软固体吞咽时平均收缩幅度显著更大（P<0.035），传播速度显著更慢（P<0.003）；（2）在正常受试者中，软固体吞咽后异常收缩比湿吞咽后更少；（3）在15名患者中，软固体吞咽诱发了湿吞咽后未观察到的非蠕动性收缩和/或极端幅度和/或持续时间的收缩；（4）在患者中，软固体吞咽后诱发异常收缩的概率显著高于湿吞咽后（P<0.0001）。我们得出结论，软固体吞咽在吞咽困难患者的研究中是有用的。
