Ludvigsson J F, Ludvigsson J
Paediatric Department, Orebro University Hospital, Orebro, Sweden.
Acta Paediatr. 2004 Nov;93(11):1474-8. doi: 10.1080/08035250410018319.
To examine the risk of low birthweight (<2500 g, LBW), intrauterine growth retardation (IUGR) and preterm birth (gestational age <37 wk) in relation to milk intake.
Observational study in southeast Sweden. Questionnaires were used to collect data on milk consumption during pregnancy and infant birthweight from mother-infant pairs during a 2-y period as part of the ABIS (All Babies in Southeast Sweden) study. Data on IUGR were obtained through the Swedish medical birth registry.
Adjusting for confounders, low milk intake during pregnancy was associated with an increased risk of IUGR (p = 0.019; n = 12880). LBW (p = 0.191) and preterm birth (p = 0.921) were not associated with milk intake during pregnancy.
This study indicates that low milk intake in the pregnant mother may be associated with IUGR of the newborn. We cannot exclude the possibility that the correlation found between milk consumption and intrauterine growth may be due to undetected confounders. Hence, further research is needed to evaluate the relationship between low milk intake, birthweight and risk of IUGR.
研究牛奶摄入量与低出生体重（<2500克，LBW）、宫内生长受限（IUGR）及早产（孕周<37周）风险之间的关系。
在瑞典东南部进行的观察性研究。作为ABIS（瑞典东南部所有婴儿）研究的一部分，采用问卷调查收集了2年期间母婴对孕期牛奶摄入量及婴儿出生体重的数据。通过瑞典医学出生登记处获取宫内生长受限的数据。
校正混杂因素后，孕期牛奶摄入量低与宫内生长受限风险增加相关（p = 0.019；n = 12880）。低出生体重（p = 0.191）和早产（p = 0.921）与孕期牛奶摄入量无关。
本研究表明，孕妇牛奶摄入量低可能与新生儿宫内生长受限有关。我们不能排除牛奶摄入量与宫内生长之间的相关性可能是由于未检测到的混杂因素所致的可能性。因此，需要进一步研究来评估低牛奶摄入量、出生体重与宫内生长受限风险之间的关系。
