Mafina-Mienandi M C, Ganga-Zandzou P S, Makoumbou P, Malonga H, Ekoundzola J R, Mayanda H F
Service de Néonatologie, Brazzaville, BP 32, Congo.
J Gynecol Obstet Biol Reprod (Paris). 2002 Sep;31(5):500-5.
A case-control study was performed between April 1st and September 30th to investigate determinants of intrauterine growth retardation (IUGR) in 3 centers in Brazzaville, Congo. Each patient group included 539 neonates. Cases were newborns with birth weight below the 10th percentile of the Leroy and Lefort curve. Risk factors of IUGR identified with univariate analysis were: maternal age<20 years, low educational level, unmarried woman, low social and economic status, primiparity, low birthweight of previous child, low interpregnancy interval, number of prenatal examinations<4, maternal weight gain during pregnancy<5kg and malaria. Multivariate analysis retained 3 risk factors: low educational level, low social and economic status, and maternal weight gain during pregnancy<5kg. This study enabled us to identify certain risk factors of IUGR useful for establishing a prevention strategy.
4月1日至9月30日期间，在刚果布拉柴维尔的3个中心开展了一项病例对照研究，以调查宫内生长受限（IUGR）的决定因素。每个患者组包括539名新生儿。病例为出生体重低于勒鲁瓦和勒福尔曲线第10百分位数的新生儿。单因素分析确定的IUGR危险因素有：母亲年龄<20岁、教育水平低、未婚女性、社会经济地位低、初产、前一个孩子出生体重低、妊娠间隔短、产前检查次数<4次、孕期母亲体重增加<5kg以及疟疾。多因素分析保留了3个危险因素：教育水平低、社会经济地位低以及孕期母亲体重增加<5kg。本研究使我们能够确定某些对制定预防策略有用的IUGR危险因素。
