Baylson F Ariella, Nyirjesy Paul, Weitz M Velma
Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Obstet Gynecol. 2004 Nov;104(5 Pt 1):931-2. doi: 10.1097/01.AOG.0000141551.67833.06.
Recurrent bacterial vaginosis is a difficult clinical condition. In women with recurrent bacterial vaginosis, relapses are common, even after prolonged courses of maintenance therapy. Because of its spectrum of activity, tinidazole was used in a patient with recurrent bacterial vaginosis.
A 23-year-old woman taking oral contraceptives had a single sexual partner. She was treated for recurrent bacterial vaginosis with multiple courses of metronidazole gel 0.75%, including regimens of maintenance therapy. The patient experienced repeated recurrences shortly after stopping treatment. A single course of oral tinidazole resulted in a prolonged period where she was free of bacterial vaginosis.
Treatment options for recurrent bacterial vaginosis are currently limited. Tinidazole may be a useful option in women with recurrent bacterial vaginosis.
复发性细菌性阴道病是一种临床难题。在患有复发性细菌性阴道病的女性中,即便经过长时间的维持治疗疗程,复发仍很常见。由于替硝唑的活性谱,其被用于一名复发性细菌性阴道病患者。
一名23岁服用口服避孕药且只有单一性伴侣的女性。她接受了多个疗程的0.75%甲硝唑凝胶治疗复发性细菌性阴道病,包括维持治疗方案。该患者在停止治疗后不久就反复复发。单疗程口服替硝唑使她在较长一段时间内未患细菌性阴道病。
目前复发性细菌性阴道病的治疗选择有限。替硝唑对于患有复发性细菌性阴道病的女性可能是一种有用的选择。