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用于热疗应用的磁性与水凝胶复合材料。

Magnetic and hydrogel composite materials for hyperthermia applications.

作者信息

Lao L L, Ramanujan R V

机构信息

School of Materials Engineering, Nanyang Technological University, Singapore 639798.

出版信息

J Mater Sci Mater Med. 2004 Oct;15(10):1061-4. doi: 10.1023/B:JMSM.0000046386.78633.e5.

DOI:10.1023/B:JMSM.0000046386.78633.e5
PMID:15516865
Abstract

Micron-sized magnetic particles (Fe3O4) were dispersed in a polyvinyl alcohol hydrogel to study their potential for hyperthermia applications. Heating characteristics of this ferrogel in an alternating magnetic field (375 kHz) were investigated. The results indicate that the amount of heat generated depends on the Fe3O4 content and magnetic field amplitude. A stable maximum temperature ranging from 43 to 47 degrees C was successfully achieved within 5-6 min. The maximum temperature was a function of Fe3O4 concentration. A specific absorption rate of up to 8.7 W/g Fe3O4 was achieved; this value was found to depend on the magnetic field strength. Hysteresis loss is the main contribution to the heating effect experienced by the sample.

摘要

微米级磁性颗粒(Fe3O4)分散在聚乙烯醇水凝胶中,以研究其在热疗应用中的潜力。研究了这种铁凝胶在交变磁场(375 kHz)中的加热特性。结果表明,产生的热量取决于Fe3O4含量和磁场强度。在5 - 6分钟内成功实现了43至47摄氏度的稳定最高温度。最高温度是Fe3O4浓度的函数。实现了高达8.7 W/g Fe3O4的比吸收率;发现该值取决于磁场强度。磁滞损耗是样品产生加热效应的主要原因。

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