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高危人群中德尔塔病毒感染的流行情况及乙型肝炎病毒相关肝病

Prevalence of delta virus infection in high risk population and hepatitis B virus related liver diseases.

作者信息

Amarapurkar D N, Vishwanath N, Kumar A, Shankaran S, Murti P, Kalro R H, Desai H G

机构信息

Department of Gastroenterology, BYL Nair Ch Hospital, Bombay.

出版信息

Indian J Gastroenterol. 1992 Jan;11(1):11-2.

PMID:1551704
Abstract

Two hundred and fifty four high risk persons or patients with hepatitis B virus related liver disease (209 men, 45 women; age range 1-78 years) were tested for anti-delta antibody and IgM anti-HBc to determine the prevalence of delta agent coinfection and superinfection. The prevalence of delta infection was as follows: acute viral hepatitis 23/148 (16%) and chronic liver disease 17/92 (19%), and asymptomatic HBsAg carriers 1/6 (17%). In the high risk population, the delta antibody prevalence was as follows: multiple transfusion recipients 3/8 (38%), patients with chronic renal failure 1/5 (20%) and medical professionals 2/7 (29%). Of 44 patients (34 men, 10 women; age 3-63 years) with delta infection, 26 (59%) had coinfection and 18 (41%) had superinfection. Six patients with anti-delta antibody had received blood transfusion(s) and six others gave history of parenteral exposure.

摘要

对254名高危人群或乙肝病毒相关肝病患者(209名男性,45名女性;年龄范围1 - 78岁)进行了丁型肝炎抗体和IgM抗-HBc检测,以确定丁型肝炎病毒合并感染和重叠感染的患病率。丁型肝炎感染的患病率如下:急性病毒性肝炎为23/148(16%),慢性肝病为17/92(19%),无症状HBsAg携带者为1/6(17%)。在高危人群中,丁型肝炎抗体患病率如下:多次输血者为3/8(38%),慢性肾衰竭患者为1/5(20%),医疗专业人员为2/7(29%)。在44例丁型肝炎感染患者(34名男性,10名女性;年龄3 - 63岁)中,26例(59%)为合并感染,18例(41%)为重叠感染。6例丁型肝炎抗体阳性患者曾接受过输血,另外6例有非肠道接触史。

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Prevalence of delta virus infection in high risk population and hepatitis B virus related liver diseases.高危人群中德尔塔病毒感染的流行情况及乙型肝炎病毒相关肝病
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