Broek A P, Bargeman D, Sprengers E D, Smolders C A
University of Twente, Department of Chemical Technology, Enschede, The Netherlands.
Int J Artif Organs. 1992 Jan;15(1):25-8.
A new wet-state membrane characterization method, thermoporometry, was used to study the effect on membrane structure of commonly used sterilization methods for artificial kidney membranes. The porosity and pore size distribution of differently sterilized hollow fiber Hemophan hemodialysis membranes were determined. Also the effect of a glycerol treatment (before sterilization) on porosity and pore size distribution after sterilization was studied. Hemophan was found to have a pore size distribution of pores with radii between 1.5 and 12 nm. Most of the samples had a maximum pore volume at a pore radius of 2.5 nm, only the steam sterilized and non glycerol treated sample had a maximum pore volume at 1.5 nm. The porosity was found to vary between 14 and 31% and was dependent on the applied treatment.
一种新的湿态膜表征方法——热孔率测定法，被用于研究常用的人工肾膜灭菌方法对膜结构的影响。测定了不同灭菌方式处理的中空纤维Hemophan血液透析膜的孔隙率和孔径分布。同时还研究了（灭菌前）甘油处理对灭菌后孔隙率和孔径分布的影响。发现Hemophan的孔径分布范围为半径1.5至12纳米的孔。大多数样品在孔径为2.5纳米时具有最大孔体积，只有蒸汽灭菌且未经过甘油处理的样品在1.5纳米时具有最大孔体积。孔隙率在14%至31%之间变化，并且取决于所采用的处理方式。
