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器官移植中的术中荧光成像系统。

An intraoperative fluorescent imaging system in organ transplantation.

作者信息

Sekijima M, Tojimbara T, Sato S, Nakamura M, Kawase T, Kai K, Urashima Y, Nakajima I, Fuchinoue S, Teraoka S

机构信息

Department of Surgery III, Tokyo Women's Medical University, Tokyo, Japan.

出版信息

Transplant Proc. 2004 Sep;36(7):2188-90. doi: 10.1016/j.transproceed.2004.09.001.

Abstract

UNLABELLED

An intraoperative fluorescent imaging system (SPY system; Novadaq Technologies, Inc, Concord, Ontario, Canada) that enables vascular surgeons to confirm the location and states of the reconstructed vessels during surgery, has been developed in the field of open heart surgery. In this paper, we evaluated the usefulness of the SPY system in kidney and liver transplantation.

PATIENTS AND METHODS

SPY system visualizes arteries and grafts intraoperatively, using indocyanine green (ICG) with a portable imaging device. The modality was evaluated in 15 patients undergoing kidney (n = 13) or liver (n = 2) transplantation with respect to safety, feasibility of use, and image quality. Images were generated and acquired with a portable laser diode/infrared camera device after injection of 10 mL of ICG (2.5 mg/mL) intravenously.

RESULT

There was no complication associated with ICG injection or the imaging device. The SPY system was easily used during transplant surgery and adequately demonstrated reconstructed arteries and patency in all patients.

CONCLUSION

The intraoperative imaging system enables the surgeon to view, record, and replay real-time images of the reconstructed arteries during surgery. The system may provide useful information during surgery such as solid organ transplantation that requires vascular reconstruction.

摘要

未标注

一种术中荧光成像系统(SPY系统;加拿大安大略省康科德市的诺瓦达克技术公司)已在心脏直视手术领域得到开发,该系统能让血管外科医生在手术过程中确认重建血管的位置和状态。在本文中,我们评估了SPY系统在肾移植和肝移植中的实用性。

患者与方法

SPY系统使用便携式成像设备,通过吲哚菁绿(ICG)在术中使动脉和移植物可视化。对15例接受肾移植(n = 13)或肝移植(n = 2)的患者就安全性、使用可行性和图像质量方面对该模式进行了评估。静脉注射10 mL ICG(2.5 mg/mL)后,用便携式激光二极管/红外摄像设备生成并采集图像。

结果

未出现与ICG注射或成像设备相关的并发症。SPY系统在移植手术过程中易于使用,并且在所有患者中均能充分显示重建动脉及其通畅情况。

结论

术中成像系统能让外科医生在手术过程中查看、记录和重放重建动脉的实时图像。该系统可能在诸如需要血管重建的实体器官移植等手术过程中提供有用信息。

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