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吲哚菁绿近红外荧光成像在消化系统肿瘤手术治疗中的作用（综述）

The role of ICG NIRL fluorescence imaging in the surgical treatment of digestive system tumors (Review).

作者信息

Hu Yanxia, Wen Tingyuan, Tuo Biguang

机构信息

Department of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China.

Department of Obstetrics and Gynecology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China.

出版信息

Mol Med Rep. 2025 Jul;32(1). doi: 10.3892/mmr.2025.13546. Epub 2025 Apr 25.

DOI:10.3892/mmr.2025.13546
PMID:40280113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12059463/
Abstract

Indocyanine green (ICG) is a relatively non‑toxic fluorescent dye with a history of safe use, which has fueled the development of new applications for ICG. Research on the use of ICG near‑infrared light (NIRL) fluorescence imaging during oncologic surgery has increased, revealing its role in tumor identification and localization, lymph node navigational resection and blood perfusion assessment. The purpose of the present review was to provide a comprehensive overview of advances in the clinical application of ICG NIRL fluorescence imaging during gastrointestinal tumor surgery. The present review discusses the techniques, outcomes, limitations and key considerations necessary for clinical practice, aiming to provide a valuable resource for professionals in the field.

摘要

吲哚菁绿（ICG）是一种具有安全使用历史的相对无毒的荧光染料，这推动了ICG新应用的开发。在肿瘤手术中使用ICG近红外光（NIRL）荧光成像的研究有所增加，揭示了其在肿瘤识别与定位、淋巴结导航切除及血流灌注评估中的作用。本综述的目的是全面概述ICG NIRL荧光成像在胃肠道肿瘤手术临床应用中的进展。本综述讨论了临床实践所需的技术、结果、局限性及关键注意事项，旨在为该领域的专业人员提供有价值的参考资料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92b/12059463/5cf26913b870/mmr-32-01-13546-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92b/12059463/86e264454524/mmr-32-01-13546-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92b/12059463/5cf26913b870/mmr-32-01-13546-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92b/12059463/86e264454524/mmr-32-01-13546-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92b/12059463/5cf26913b870/mmr-32-01-13546-g01.jpg

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Structure-Inherent Tumor-Targeted IR-783 for Near-Infrared Fluorescence-Guided Photothermal Therapy.结构固有肿瘤靶向 IR-783 用于近红外荧光引导光热治疗。
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