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孟加拉国达卡一家城市医院中产超广谱β-内酰胺酶的大肠杆菌和肺炎克雷伯菌的患病率。

Prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in an urban hospital in Dhaka, Bangladesh.

作者信息

Rahman M Mushfequr, Haq J Ashraful, Hossain M Akram, Sultana Rosy, Islam Faridul, Islam A H M Shafiqul

机构信息

Department of Immunology and Microbiology, National Healthcare Network, 69/M, Panthopath, Dhaka1205, Bangladesh.

出版信息

Int J Antimicrob Agents. 2004 Nov;24(5):508-10. doi: 10.1016/j.ijantimicag.2004.05.007.

Abstract

The prevalence of extended-spectrum beta-lactamases (ESBL)-producing organisms in an urban hospital in Dhaka City was assessed over a 10-month period. A double disk test was performed to detect ESBL-producing Escherichia coli and Klebsiella pneumoniae. 43.2% and 39.5% of E. coli and K. pneumoniae had ESBL phenotypes, respectively. The combination of augmentin with ceftazidime detected the most ESBL-producing E. coli (39.5%) while augmentin with ceftriaxone was the best combination for the detection of ESBL (31.6%) in K. pneumoniae.

摘要

在达卡市的一家城市医院,对10个月期间产超广谱β-内酰胺酶(ESBL)的微生物的流行情况进行了评估。采用双纸片试验检测产ESBL的大肠埃希菌和肺炎克雷伯菌。大肠埃希菌和肺炎克雷伯菌分别有43.2%和39.5%具有ESBL表型。阿莫西林/克拉维酸与头孢他啶联合检测出产ESBL大肠埃希菌的比例最高(39.5%),而阿莫西林/克拉维酸与头孢曲松联合是检测肺炎克雷伯菌中ESBL的最佳组合(31.6%)。

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