改良间接血凝试验用于检测指尖血中的梅毒螺旋体抗体。
Modified indirect hemagglutination test for detection of treponemal antibodies in finger-prick blood.
作者信息
Backhouse J L, Lee M H, Nesteroff S I, Hudson B J, Hamilton P A
机构信息
Institute of Clinical Pathology and Medical Research, Westmead, New South Wales, Australia.
出版信息
J Clin Microbiol. 1992 Mar;30(3):561-3. doi: 10.1128/jcm.30.3.561-563.1992.
A modified indirect hemagglutination test for the detection of treponemal antibodies was developed for use with finger-prick blood. By using paired serum and absorbed finger-prick blood from 58 patients from an area previously endemic for yaws and 12 patients without yaws, the modified hemagglutination test was compared with a hemagglutination test for Treponema pallidum and the fluorescent treponemal antibody absorption test. The modified hemagglutination test showed 100% specificity and an overall agreement of 96.5% with the hemagglutination test for T. pallidum and 94.8% with the fluorescent treponemal antibody test. The modified hemagglutination test appears to be a simple and economical test that is suitable for use in large epidemiological surveys for yaws.
开发了一种用于检测梅毒螺旋体抗体的改良间接血凝试验，以用于手指采血。通过使用来自先前雅司病流行地区的58例患者和12例无雅司病患者的配对血清及吸收的手指采血，将改良血凝试验与梅毒螺旋体血凝试验和荧光梅毒螺旋体抗体吸收试验进行比较。改良血凝试验显示特异性为100%，与梅毒螺旋体血凝试验的总体一致性为96.5%，与荧光梅毒螺旋体抗体试验的总体一致性为94.8%。改良血凝试验似乎是一种简单且经济的试验，适用于大规模雅司病流行病学调查。
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