荧光密螺旋体抗体吸收试验、梅毒螺旋体抗体微量血凝试验和梅毒血凝试验之间的特异性、敏感性和可重复性。
Specificity, sensitivity, and reproducibility among the fluorescent treponemal antibody-absorption test, the microhemagglutination assay for Treponema pallidum antibodies, and the hemagglutination treponemal test for syphilis.
作者信息
Larsen S A, Hambie E A, Pettit D E, Perryman M W, Kraus S J
出版信息
J Clin Microbiol. 1981 Oct;14(4):441-5. doi: 10.1128/jcm.14.4.441-445.1981.
Abstract
Using 920 sera, we compared the specificity and reproducibility of the hemagglutination treponemal test for syphilis with those of the fluorescent treponemal antibody-absorption test and the microhemagglutination assay for Treponema pallidum antibodies; we found all three tests to be comparable. However, the hemagglutination treponemal test for syphilis, like the microhemagglutination assay for T. pallidum antibodies, lacked sensitivity in sera from patients with primary syphilis.
摘要
我们使用920份血清，比较了梅毒血凝密螺旋体试验与荧光密螺旋体抗体吸收试验以及梅毒螺旋体抗体微量血凝试验的特异性和可重复性；我们发现这三种试验具有可比性。然而，梅毒血凝密螺旋体试验，如同梅毒螺旋体抗体微量血凝试验一样，在一期梅毒患者的血清中缺乏敏感性。
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本文引用的文献
1
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J Clin Microbiol. 1980 Oct;12(4):629-30. doi: 10.1128/jcm.12.4.629-630.1980.
2
Haemagglutination test utilizing pathogenic Treponema pallidum for the sero-diagnosis of syphilis.
Br J Vener Dis. 1967 Sep;43(3):181-5. doi: 10.1136/sti.43.3.181.
3
Hemagglutination tests and related advances in serodiagnosis of syphilis.
Arch Dermatol. 1974 Jun;109(6):854-7.
4
Treponemal haemagglutination test.
Br J Vener Dis. 1973 Jun;49(3):242-8. doi: 10.1136/sti.49.3.242.
5
Comparison of a hemagglutination treponemal test for syphilis (HATTS) with other serologic methods for the diagnosis of syphilis.
Sex Transm Dis. 1978 Jul-Sep;5(3):103-14. doi: 10.1097/00007435-197807000-00005.
6
False-positive reactions in the rapid plasma reagin-card, fluorescent treponemal antibody-absorbed, and hemagglutination treponemal syphilis serology tests.
J Clin Microbiol. 1979 Mar;9(3):369-72. doi: 10.1128/jcm.9.3.369-372.1979.
7
Hemagglutination tests for syphilis antibody.
Am J Clin Pathol. 1978 Aug;70(2):230-3. doi: 10.1093/ajcp/70.2.230.
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