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从一名艾滋病患者的滑液中分离出一种新型黄色分枝杆菌序列变种。

Isolation of a novel sequevar of Mycobacterium flavescens from the synovial fluid of an AIDS patient.

作者信息

Tortoli E, Rindi L, Bartoloni A, Garzelli C, Manfrin V, Mantella A, Piccoli P, Scarparo C

机构信息

Regional Reference Centre for Mycobacteria, Microbiology and Virology Laboratory, Careggi Hospital, Florence, Italy.

出版信息

Clin Microbiol Infect. 2004 Nov;10(11):1017-9. doi: 10.1111/j.1469-0961.2004.00947.x.

Abstract

This report describes the characterisation of a mycobacterium involved in a case of septic arthritis in an AIDS patient that was treated successfully with specific anti-mycobacterial drugs. The biochemical and cultural features, and the mycolic acid pattern as assessed by high-performance liquid chromatography, were fully compatible with the isolate being Mycobacterium flavescens. However, the isolate's 16S rDNA sequence differed by five nucleotides from the two known sequevars of M. flavescens, thus indicating that this isolate belonged to a new 16S rDNA sequevar.

摘要

本报告描述了一名艾滋病患者发生的脓毒性关节炎病例中所涉及的一种分枝杆菌的特征,该患者经特异性抗分枝杆菌药物治疗成功。通过高效液相色谱评估的生化和培养特征以及分枝菌酸模式,与分离株为微黄分枝杆菌完全相符。然而,该分离株的16S rDNA序列与微黄分枝杆菌的两个已知序列变体有五个核苷酸的差异,因此表明该分离株属于一个新的16S rDNA序列变体。

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