Bartels Matthew N, Jelic Sanja, Ngai Pakkay, Gates Gregory, Newandee Douglas, Reisman Stanley S, Basner Robert C, De Meersman Ronald E
Department of Rehabilitation Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, Box 38, New York, NY 10032, USA.
Respir Physiol Neurobiol. 2004 Nov 30;144(1):91-8. doi: 10.1016/j.resp.2004.08.002.
Heart rate variability (HRV) and systolic blood pressure variability (BPV) during incremental exercise at 50, 75, and 100% of previously determined ventilatory threshold (VT) were compared to that of resting controlled breathing (CB) in 12 healthy subjects. CB was matched with exercise-associated respiratory rate, tidal volume, and end-tidal CO(2) for all stages of exercise. Power in the low frequency (LF, 0.04-0.15 Hz) and high frequency (HF, >0.15-0.4 Hz) for HRV and BPV were calculated, using time-frequency domain analysis, from beat-to-beat ECG and non-invasive radial artery blood pressure, respectively. During CB absolute and normalized power in the LF and HF of HRV and BPV were not significantly changed from baseline to maximal breathing. Conversely, during exercise HRV, LF and HF power significantly decreased from baseline to 100% VT while BPV, LF and HF power significantly increased for the same period. These findings suggest that the increases in ventilation associated with incremental exercise do not significantly affect spectral analysis of cardiovascular autonomic modulation in healthy subjects.
在12名健康受试者中，将递增运动期间心率变异性（HRV）和收缩压变异性（BPV）与静息控制呼吸（CB）的心率变异性和收缩压变异性进行比较，递增运动强度为先前确定的通气阈值（VT）的50%、75%和100%。在运动的各个阶段，CB的呼吸频率、潮气量和呼气末二氧化碳与运动相关的呼吸频率、潮气量和呼气末二氧化碳相匹配。分别使用时频域分析，根据逐搏心电图和无创桡动脉血压计算HRV和BPV的低频（LF，0.04 - 0.15Hz）和高频（HF，>0.15 - 0.4Hz）功率。在CB期间，HRV和BPV的LF和HF中的绝对功率和标准化功率从基线到最大呼吸均无显著变化。相反，在运动期间，HRV的LF和HF功率从基线到100%VT显著降低，而BPV的LF和HF功率在同一时期显著增加。这些发现表明，与递增运动相关的通气增加不会显著影响健康受试者心血管自主调节的频谱分析。
