Bamford Joel T M, Gessert Charles E, Renier Colleen M
Department of Dermatology, St. Mary's/Duluth Clinic Health System, Duluth, MN 55805-1983, USA.
J Am Acad Dermatol. 2004 Nov;51(5):697-703. doi: 10.1016/j.jaad.2004.04.013.
There are no standardized measures for the severity of rosacea.
To determine what clinical signs correlate best with global severity of rosacea, and to examine inter-rater reliability. Methods Four clinicians each made 82 assessments of rosacea patients. Each assessment used 60 0-to-10 Likert-like scales for the signs of rosacea. Subjects also assessed the severity of their rosacea.
The clinicians' assessment of global severity correlated strongly with erythema, especially on the cheeks. Subjects' assessment of global severity correlated more strongly with papules/pustules. Different methods of assessing severity--estimation of area involved, intensity, or lesion counts--did not produce significantly different results. Inter-rater reliability was low on 11-point (0-10) scales, but improved when scales were collapsed to 5 or 4 points.
Clinicians and patients assess severity of rosacea differently, with clinicians focusing on erythema and patients focusing on papules/pustules. New instruments for assessing severity must address inter-rater reliability.
酒渣鼻严重程度尚无标准化测量方法。
确定哪些临床体征与酒渣鼻的整体严重程度最相关,并检验评估者间的可靠性。方法:四位临床医生对酒渣鼻患者各进行82次评估。每次评估使用60个0至10的类李克特量表来评估酒渣鼻的体征。受试者也对自己酒渣鼻的严重程度进行评估。
临床医生对整体严重程度的评估与红斑密切相关,尤其是脸颊部位的红斑。受试者对整体严重程度的评估与丘疹/脓疱的相关性更强。评估严重程度的不同方法——受累面积估计、强度或皮损计数——并未产生显著不同的结果。在11分(0至10)量表上,评估者间的可靠性较低,但当量表合并为5分或4分时有所改善。
临床医生和患者对酒渣鼻严重程度的评估不同,临床医生关注红斑,而患者关注丘疹/脓疱。评估严重程度的新工具必须解决评估者间的可靠性问题。