Agaba E I, Agaba P A, Wigwe C M
Department of Medicine, Jos University Teaching Hospital, Jos, Nigeria.
Niger J Med. 2004 Oct-Dec;13(4):379-82.
Chronic consumption of analgesics has been shown to increase the risk of end-stage renal disease. In Nigeria, these drugs are readily available as there is no legislation regulating their consumption. We report the use and abuse of analgesics in a Nigerian population.
Using a pre-tested questionnaire, subjects in Zawan B ward in Jos were interviewed regarding analgesic use. Cumulative lifetime dose of drugs consumed was calculated by obtaining the product of the average number of pills consumed in a week by duration of use in years. Analgesic abuse was defined as cumulative lifetime use of >5000 pills.
Common analgesics regularly consumed were paracetamol in 58.1%, analgesic mixtures 28.9% and NSAIDS 13%. Common indications for use of these drugs were musculoskeletal pains, headache, fever and stress. Analgesic abuse was present in 22.6% of the respondents.
Analgesic abuse is common in Jos, Nigeria. The sale and consumption of these drugs should be restricted by legislation.
长期服用镇痛药已被证明会增加终末期肾病的风险。在尼日利亚，由于没有立法对这些药物的消费进行监管，这些药物很容易获得。我们报告了尼日利亚人群中镇痛药的使用和滥用情况。
使用预先测试的问卷，对乔斯扎万B区病房的受试者进行了关于镇痛药使用情况的访谈。通过将每周平均服用药丸数量乘以使用年限来计算累计终身药物剂量。镇痛药滥用被定义为累计终身使用超过5000粒药丸。
经常服用的常见镇痛药中，对乙酰氨基酚占58.1%，镇痛合剂占28.9%，非甾体抗炎药占13%。使用这些药物的常见适应症是肌肉骨骼疼痛、头痛、发烧和压力。22.6%的受访者存在镇痛药滥用情况。
镇痛药滥用在尼日利亚的乔斯很常见。这些药物的销售和消费应通过立法加以限制。
