Li Huanyu, Deng Hongzhu, Wang Caiyun
Guangzhou Sanatorium of PLA, Guangzhou 510515.
Zhong Yao Cai. 2004 Jun;27(6):430-2.
To study the therapeutic effect of niaozhuoqing on minimal change nephropathy (MCN) in rats.
The MCN rat model was induced by intravenous injection of adriamycin. The effect of treatment on 24h urine protein, serum protein, lipid metabolism, malondialdehyde (MDA), superoxide dismutase (SOD) in serum, and renal histopathological changes were observed.
Niaozhuoqing could decrease the contents of proteinuria, blood lipid and MDA in serum, increase serum protein, SOD level and pathologically restore the glomeruli.
Niaozhuoqing has good effects on MCN, which probably related to decrease serum lipids level and reduce oxygen free radicals.
研究尿浊清对大鼠微小病变肾病（MCN）的治疗作用。
通过静脉注射阿霉素诱导建立MCN大鼠模型。观察治疗对24小时尿蛋白、血清蛋白、脂质代谢、血清丙二醛（MDA）、超氧化物歧化酶（SOD）以及肾脏组织病理学变化的影响。
尿浊清可降低血清中蛋白尿、血脂和MDA的含量，提高血清蛋白、SOD水平，并使肾小球病理恢复。
尿浊清对MCN有良好疗效，可能与降低血脂水平和减少氧自由基有关。
