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[定居于健康人上呼吸道的革兰氏阴性杆菌的疏水性]

[Hydrophobic properties of gram-negative rods colonizing upper respiratory tract of healthy people].

作者信息

Loś Renata, Malm Anna, Biernasiuk Anna, Korona-Głowniak Izabela, Kosikowska Urszula

机构信息

Zakład Mikrobiologii Farmaceutycznej AM w Lublinie.

出版信息

Med Dosw Mikrobiol. 2004;56(1):57-65.

PMID:15524397
Abstract

The cell surface hydrophobicity is one of the non specific factors of adhesion influencing the ability of microorganisms to colonize nasopharynx. The aim of this paper was to evaluate via salt aggregation test (SAT) the cell surface hydrophobicity of 150 strains of gram-negative rods isolated from the throat or/and nasal specimens of healthy people. It has been found that among the nonfermenting rods hydrophobic strains were predominant. In contrast, the isolates of Enterobacteriaceae family were characterized by the distinctive features of the cell surface within particular genera or even species. The obtained results show that, despite differences in cell surface hydrophobicity, numerous species of gram-negative rods have the ability to colonize the mucous membrane of upper respiratory tract. This suggests that the cell surface hydrophobicity is rather a feature of species or genus, but it is not related to the ecological niche of microorganisms in human body.

摘要

细胞表面疏水性是影响微生物在鼻咽部定植能力的非特异性黏附因素之一。本文旨在通过盐聚集试验(SAT)评估从健康人的咽喉或/和鼻腔标本中分离出的150株革兰氏阴性杆菌的细胞表面疏水性。研究发现,在非发酵菌中,疏水菌株占主导地位。相比之下,肠杆菌科的分离株在特定属甚至种内具有独特的细胞表面特征。所得结果表明,尽管细胞表面疏水性存在差异,但许多革兰氏阴性杆菌种类都有在上呼吸道黏膜定植的能力。这表明细胞表面疏水性更像是一个物种或属的特征,但与微生物在人体中的生态位无关。

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