酵母中的线粒体程序性细胞死亡途径
Mitochondrial programmed cell death pathways in yeast.
作者信息
Hardwick J Marie, Cheng Wen-Chih
机构信息
Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, MD 21205, USA.
出版信息
Dev Cell. 2004 Nov;7(5):630-2. doi: 10.1016/j.devcel.2004.10.013.
PMID:15525523
Abstract
Whether or not yeast cell death is altruistic, apoptotic, or otherwise analogous to programmed cell death in mammals is controversial. However, growing attention to cell death mechanisms in yeast has produced several new papers that make a case for ancient origins of programmed death involving mitochondrial pathways conserved between yeast and mammals.
摘要
酵母细胞死亡是否是利他性的、凋亡性的，或者在其他方面类似于哺乳动物的程序性细胞死亡，这是有争议的。然而，对酵母细胞死亡机制的日益关注催生了几篇新论文，这些论文论证了程序性死亡的古老起源，涉及酵母和哺乳动物之间保守的线粒体途径。
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