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Medical therapy for ulcerative colitis: the state of the art and beyond.

作者信息

Ross Andrew S, Cohen Russell D

机构信息

Department of Medicine, Section of Gastroenterology, The University of Chicago Hospitals, 5841 S. Maryland Avenue, MC 4076, Chicago, IL 60637, USA.

出版信息

Curr Gastroenterol Rep. 2004 Dec;6(6):488-95. doi: 10.1007/s11894-004-0071-9.

DOI:10.1007/s11894-004-0071-9
PMID:15527679
Abstract

Ulcerative colitis (UC) is an idiopathic inflammatory condition of the large intestine. Recent advances in our understanding of the pathogenesis of UC have led to the development of novel treatments for this often debilitating condition. Aside from aminosalicylates and corticosteroids, drugs that have been used for decades in the treatment of UC, biologic agents, in addition to medications targeting specific effector mechanisms involved in the inflammatory cascade, have been used in patients with UC with varying degrees of success. Clinicians have never had as many therapeutic options for UC as they do today. Herein we review the variety of treatment options, both standard and investigational, that are available for patients with UC.

摘要

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Delay of the first onset of pouchitis by oral intake of the probiotic strain Lactobacillus rhamnosus GG.通过口服益生菌菌株鼠李糖乳杆菌GG延迟袋炎的首次发病。
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Anti-Inflammatory Effects of Huangqin Decoction on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice Through Regulation of the Gut Microbiota and Suppression of the Ras-PI3K-Akt-HIF-1α and NF-κB Pathways.黄芩汤通过调节肠道菌群及抑制Ras-PI3K-Akt-HIF-1α和NF-κB信号通路对葡聚糖硫酸钠诱导的小鼠溃疡性结肠炎的抗炎作用
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Gastroenterol Res Pract. 2019 Aug 19;2019:8536952. doi: 10.1155/2019/8536952. eCollection 2019.
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