Vahid A, Hadjati J, Kermanshah H, Ghabraei S
Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Nov;98(5):619-21. doi: 10.1016/j.tripleo.2004.04.005.
Dentin Bonding Agents (DBAs) have been proposed as root-end filling materials. This study examined the effect of polymerized DBAs on human monocyte viability.
Monocytes were directly isolated from peripheral blood and being exposed to cured Scotch bond I (Single Bond) and Prime & Bond in different time intervals (36 and 72 hours). The viability of monocytes was determined by MTT assay.
Viability of the cells was time dependent. There was no significant difference between the effect of 2 DBAs on monocytes.
Results indicate that DBAs in polymerized form can alter the viability of monocytes and decrease it within time.
牙本质粘结剂（DBA）已被提议作为根尖倒充填材料。本研究检测了聚合型DBA对人单核细胞活力的影响。
直接从外周血中分离单核细胞，并使其在不同时间间隔（36小时和72小时）暴露于固化后的Scotch bond I（单键）和Prime & Bond。通过MTT法测定单核细胞的活力。
细胞活力具有时间依赖性。两种DBA对单核细胞的作用之间无显著差异。
结果表明，聚合形式的DBA可改变单核细胞的活力，并随时间降低其活力。
