Burkhard-Meier C, Schneider T I, Baer F M
MMW Fortschr Med. 2004 Aug 5;146(31-32):38-40.
Endothelial dysfunction is a "systemic disease" and a predictor of preclinical atherosclerosis. A relatively simple-to-perform and reliable diagnostic method of evaluating endothelial function is the measurement of the forearm blood flow (FBF). Unremarkable vasoreactivity of the brachial artery on performing FBF measurement is a prognostically favorable sign. This applies equally to patients with cardiovascular risk factors such as hypertension, hyperlipidemia or diabetes mellitus, and to patients with angina pectoris. A number of investigations suggest that cardiovascular endpoints can be significantly diminished by reducing the risk factors.
内皮功能障碍是一种“全身性疾病”，也是临床前期动脉粥样硬化的一个预测指标。评估内皮功能的一种相对简单易行且可靠的诊断方法是测量前臂血流量（FBF）。在进行FBF测量时肱动脉血管反应不明显是一个预后良好的迹象。这同样适用于患有高血压、高脂血症或糖尿病等心血管危险因素的患者以及心绞痛患者。多项研究表明，通过降低危险因素可显著减少心血管终点事件。
