Ades Sarah E
Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Curr Biol. 2004 Nov 9;14(21):R924-6. doi: 10.1016/j.cub.2004.10.015.
The ClpXP protease of bacteria can degrade a wide variety of proteins while maintaining remarkable substrate selectivity. New work in Escherichia coli implicates adaptor proteins in enhancing substrate selectivity and regulating the flow of substrates to cellular proteases.
细菌的ClpXP蛋白酶能够降解多种蛋白质，同时保持显著的底物选择性。大肠杆菌中的新研究表明，衔接蛋白在增强底物选择性和调节底物向细胞蛋白酶的流动中发挥作用。
