[系统性红斑狼疮与甲状腺功能减退症的关联。病例报告]

[The association of systemic lupus erythematosus and hypothyroidism. A case report].

作者信息

Chaabouni Lilia, El-Manaa Khadija, Ben Haj Yahia Chiraz, Abdelmoula Leila, Kchir Mohamed Montacer, Zouari Rafik

机构信息

Service de Rhumatologie E.P.S. Charles Nicolle, Tuni, Tunisie.

出版信息

Tunis Med. 2004 Aug;82(8):796-8.

PMID:15532779

Abstract

The association of systemic lupus erythematosus (SLE) and hypothyroidism is uncommon, and concerns essentially the autoimmun thyroiditis. However, the coexistence SLE-primary hypothyroidism is exceptional. We report an observation of 25-old woman, who presents a clinical form of hypothyroidism, confirmed by hormonal tests, and which is associated to polyarthritis and proximal myopathy non ameliorated by opotherapy. The explorations conclude in SLE. A favourable evolution of muscular and articular signs is obtained with corticotherapy.

摘要

系统性红斑狼疮（SLE）与甲状腺功能减退症的关联并不常见，主要涉及自身免疫性甲状腺炎。然而，SLE合并原发性甲状腺功能减退症的情况极为罕见。我们报告了一例25岁女性病例，该患者呈现出甲状腺功能减退的临床症状，经激素检测得以证实，且伴有多关节炎和近端肌病，药物治疗效果不佳。各项检查结果确诊为SLE。采用皮质激素治疗后，肌肉和关节症状得到了良好改善。