Benjamin E, Wong D K K, Choa D
Royal National Throat Nose and Ear Hospital, London, UK.
Clin Otolaryngol Allied Sci. 2004 Dec;29(6):582-7. doi: 10.1111/j.1365-2273.2004.00894.x.
General anaesthesia, often causes a widespread vasodilation, producing a hyperaemic nasal mucosa, hence the need for a topical application to decongest the nose and reduce the nasal blood flow to optimize the operative field. The use of a combination of cocaine, sodium bicarbonate and adrenaline given the eponymous title of 'Moffett's Solution' is standard practice in many rhinological procedures to provide local anaesthesia, vasoconstriction and decongestion. We discuss each component of 'Moffett's' reviewing the science and evidence behind its usage and the huge variation in the techniques of its application.
全身麻醉常常会导致广泛的血管扩张，使鼻黏膜充血，因此需要局部用药来减轻鼻充血并减少鼻腔血流，以优化手术视野。使用可卡因、碳酸氢钠和肾上腺素的组合，即所谓的“莫菲特溶液”，在许多鼻科手术中是提供局部麻醉、血管收缩和减轻充血的标准做法。我们将讨论“莫菲特溶液”的每个成分，回顾其使用背后的科学和证据以及其应用技术的巨大差异。
