Department of Otolaryngology, University of Colorado, Aurora, CO 80045, USA.
Curr Allergy Asthma Rep. 2011 Jun;11(3):220-9. doi: 10.1007/s11882-011-0182-y.
Current research has only reinforced the belief that chronic rhinosinusitis is a multifactorial and idiosyncratic disease process. Most basic science research on the topic focuses on delineating the many proposed contributing factors and attempting to establish therapeutic targets. In patients whose symptoms do not respond to medical therapy, endoscopic sinus surgery may be offered. Several surgical techniques have been proposed, and it would appear that certain techniques are ideal for certain situations. Recent clinical research has focused on the introduction of new technology and new techniques. Additionally, investigators have looked for ways to optimize current techniques and to determine which patient populations may expect to benefit from which types of interventions.
目前的研究只是进一步证实了慢性鼻-鼻窦炎是一种多因素且因人而异的疾病过程。该主题的大多数基础科学研究都集中在描述许多提出的致病因素并尝试确定治疗靶点上。对于那些对药物治疗无反应的患者，可以提供鼻内镜鼻窦手术。已经提出了几种手术技术，而且某些技术似乎适用于某些特定情况。最近的临床研究侧重于新技术和新方法的引入。此外，研究人员还在寻找优化现有技术的方法，并确定哪些患者群体可能从哪种干预措施中受益。
