Institute of Automation, Chinese Academy of Sciences, Beijing, People's Republic of China.
University of Chinese Academy of Sciences, Beijing, People's Republic of China.
J Clin Sleep Med. 2021 May 1;17(5):1031-1038. doi: 10.5664/jcsm.9094.
For surgical treatment of patients with obstructive sleep apnea-hypopnea syndrome, it is crucial to locate accurately the obstructive sites in the upper airway; however, noninvasive methods for locating the obstructive sites have not been well explored. Snoring, as the cardinal symptom of obstructive sleep apnea-hypopnea syndrome, should contain information that reflects the state of the upper airway. Through the classification of snores produced at four different locations, this study aimed to test the hypothesis that snores generated by various obstructive sites differ.
We trained and tested our model on a public data set that comprised 219 participants. For each snore episode, an acoustic and a physiological feature were extracted and concatenated, forming a 59-dimensional fusion feature. A principal component analysis and a support machine vector were used for dimensional reduction and snore classification. The performance of the proposed model was evaluated using several metrics: sensitivity, precision, specificity, area under the receiver operating characteristic curve, and F1 score.
The unweighted average values of sensitivity, precision, specificity, area under the curve, and F1 were 86.36%, 89.09%, 96.4%, 87.9%, and 87.63%, respectively. The model achieved 98.04%, 80.56%, 72.73%, and 94.12% sensitivity for types V (velum), O (oropharyngeal), T (tongue), and E (epiglottis) snores.
The characteristics of snores are related to the state of the upper airway. The machine-learning-based model can be used to locate the vibration sites in the upper airway.
对于阻塞性睡眠呼吸暂停低通气综合征患者的手术治疗,准确定位上气道的阻塞部位至关重要;然而,尚未充分探索用于定位阻塞部位的非侵入性方法。打鼾是阻塞性睡眠呼吸暂停低通气综合征的主要症状,应该包含反映上气道状态的信息。通过对四个不同部位产生的鼾声进行分类,本研究旨在检验以下假设,即来自不同阻塞部位的鼾声存在差异。
我们在一个包含 219 名参与者的公共数据集上对模型进行了训练和测试。对于每个鼾声事件,提取了声学和生理特征,并将它们串联起来,形成一个 59 维融合特征。使用主成分分析和支持向量机进行降维和鼾声分类。使用灵敏度、精确度、特异性、受试者工作特征曲线下面积和 F1 分数等多个指标来评估所提出模型的性能。
未加权平均灵敏度、精确度、特异性、曲线下面积和 F1 分别为 86.36%、89.09%、96.4%、87.9%和 87.63%。对于 V(软腭)、O(口咽)、T(舌)和 E(会厌)型鼾声,该模型的灵敏度分别为 98.04%、80.56%、72.73%和 94.12%。
鼾声的特征与上气道的状态有关。基于机器学习的模型可用于定位上气道的振动部位。