Imamura Atsushi, Matsuo Naoki, Ariki Masako, Horikoshi Hiroko, Hattori Tatsuaki
Department of Pediatrics, Gifu Prefectural Gifu Hospital, 4-6-1, Noishiki, Gifu 500-8717, Japan.
Brain Dev. 2004 Dec;26(8):535-8. doi: 10.1016/j.braindev.2004.02.006.
A case of cerebral infarction with transient cerebral arteriopathy in a 12-year-old female is described. The child showed with an acute onset of left hemiplegia, central facial palsy and aphasia. She was diagnosed with right internal carotid artery obstruction with no predisposing factors for cerebral infarction. A serial MR image and MR spectroscopy of the brain was performed. MR angiography revealed reversible vascular changes in the right middle cerebral artery after several months. The ratio of choline/creatine was elevated and that of N-acetylaspartate (NAA)/creatine was depressed in the cerebral lesion, however, they were normalized during the remission phase with long echo time-MR spectroscopy. The elevation of the lactate peak was clarified with short echo time-MR spectroscopy. The longitudinal follow up using MR angiography, and MR spectroscopy with long and short echo time was useful for the evaluation of reversible vascular change with cerebral infarction in children.
本文描述了一例12岁女性患有脑梗死并伴有短暂性脑动脉病变的病例。该患儿急性起病,表现为左侧偏瘫、中枢性面瘫和失语。她被诊断为右侧颈内动脉阻塞,且无脑梗死的诱发因素。对其进行了一系列脑部磁共振成像(MR)和磁共振波谱分析(MRS)。磁共振血管造影显示数月后右侧大脑中动脉出现可逆性血管变化。在脑损伤部位,胆碱/肌酸比值升高,N-乙酰天门冬氨酸(NAA)/肌酸比值降低,然而,在缓解期通过长回波时间磁共振波谱分析,这些指标恢复正常。通过短回波时间磁共振波谱分析明确了乳酸峰升高。使用磁共振血管造影以及长、短回波时间的磁共振波谱分析进行纵向随访,有助于评估儿童脑梗死的可逆性血管变化。