Guan Yong-Song, Sun Long, Zhou Xiang-Ping, Li Xiao, Zheng Xiao-Hua
Department of Radiology, Huaxi Hospital, Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan Province, China.
World J Gastroenterol. 2004 Dec 15;10(24):3543-8. doi: 10.3748/wjg.v10.i24.3543.
In the past decade, a variety of interventional procedures have been employed for local control of hepatocellular carcinoma (HCC). These include transcather arterial chemoembolization (TACE) and several tumour ablation techniques, such as percutaneous ethanol injection (PEI), radio-frequency ablation (RFA), or percutaneous microwave coagulation therapy (PMC), laser-induced interstitial thermotherapy (LITT), etc. For a definite assessment of the therapeutic efficacy of interventional procedures, histological examination using percutaneous needle biopsy may be the most definite assessment of the therapeutic efficacy of interventional therapy, however, it is invasive and the specimen retrieved does not always represent the entire lesion owing to sampling errors. Therefore, computed tomography (CT) and magnetic resonance imaging (MRI) play a crucial role in follow-up of HCC treated by interventional procedures, by which the local treatment efficacy, recurrent disease and some of therapy-induced complications are evaluated. Contrast enhanced axial imaging (CT or MR imaging) may be the most sensitive test for assessing the therapeutic efficacy. The goal of the review was to describe the value of CT and MRI in the evaluation of interventional treatments.
在过去十年中,已采用多种介入程序来局部控制肝细胞癌(HCC)。这些程序包括经动脉化疗栓塞术(TACE)以及几种肿瘤消融技术,如经皮乙醇注射(PEI)、射频消融(RFA)、经皮微波凝固疗法(PMC)、激光诱导间质热疗(LITT)等。为了明确评估介入程序的治疗效果,使用经皮穿刺活检进行组织学检查可能是对介入治疗效果最确切的评估,然而,它具有侵入性,并且由于采样误差,获取的标本并不总是代表整个病变。因此,计算机断层扫描(CT)和磁共振成像(MRI)在接受介入程序治疗的HCC随访中起着关键作用,通过它们可以评估局部治疗效果、复发性疾病以及一些治疗引起的并发症。对比增强轴向成像(CT或MR成像)可能是评估治疗效果最敏感的检查。本综述的目的是描述CT和MRI在评估介入治疗中的价值。