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[生殖道支原体与早产风险之间的关联]

[Association between genital mycoplasmas and risk of preterm delivery].

作者信息

Wasiela Małgorzata, Krzemiński Zbigniew, Hanke Wojciech, Kalinka Jarosław

机构信息

Zakład Mikrobiologii Lekarskiej, Katedra Mikrobiologii, Uniwersytet Medyczny w Lodzi.

出版信息

Med Wieku Rozwoj. 2003 Jul-Sep;7(3 Suppl 1):211-6.

Abstract

The main aim of this study was to determine the prevalence of maternal colonisation by genital mycoplasmas during pregnancy and to assess its association with preterm delivery. The cervical swabs of 179 pregnant women between 8 and 16 week of gestation were cultured for Mycoplasma hominis and Ureaplasma urealyticum. Clinical details and perinatal outcomes were documented. Of a total of 179 women enrolled, 68 (38.0%) had positive cervical culture for genital mycoplasmas; 30 (16.7%) for M. hominis and 38 (21.3%) for U. urealyticum. Preterm delivery occurred in 21 (11.7%) women. Genital mycoplasmas were found more frequently in group with preterm delivery as compare to women who delivered at term (p = 0.05) and its presence at lower genital tract at early pregnancy was a risk factor of preterm delivery. Early pregnancy screening for genital mycoplasmas and following treatment may reduce the rate of preterm deliveries.

摘要

本研究的主要目的是确定孕期生殖道支原体在孕妇中的定植率,并评估其与早产的相关性。对179名妊娠8至16周孕妇的宫颈拭子进行人型支原体和解脲脲原体培养。记录临床细节和围产期结局。在总共纳入的179名妇女中,68名(38.0%)宫颈生殖道支原体培养呈阳性;人型支原体阳性30名(16.7%),解脲脲原体阳性38名(21.3%)。21名(11.7%)妇女发生早产。与足月分娩的妇女相比,早产组中生殖道支原体的检出率更高(p = 0.05),且其在孕早期下生殖道的存在是早产的一个危险因素。孕早期筛查生殖道支原体并进行后续治疗可能会降低早产率。

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