Norris Angela, Dreher H Michael
Partnership Comprehensive Care Practice HIV Clinic, Drexel University, Philadelphia, PA, USA.
J Assoc Nurses AIDS Care. 2004 Nov-Dec;15(6):46-64. doi: 10.1177/1055329004271187.
Widespread use of highly active antiretroviral therapy (HAART) to manage HIV infection is now associated with the development of lipodystrophy syndrome. This syndrome is a combination of such morphologic and metabolic changes as hyperlipidemia, fat redistribution, and insulin resistance. Although many of the long-term effects of HAART have not been fully recognized, it is thought that lipodystrophy syndrome may now contribute to early-onset hypercholesterolemia, heart disease, and diabetes, and may have a negative psychological impact on the individual living with HIV infection.
目前，广泛使用高效抗逆转录病毒疗法（HAART）治疗HIV感染与脂肪代谢障碍综合征的发生有关。该综合征是高脂血症、脂肪重新分布和胰岛素抵抗等形态学和代谢变化的组合。尽管HAART的许多长期影响尚未得到充分认识，但人们认为脂肪代谢障碍综合征现在可能导致早发性高胆固醇血症、心脏病和糖尿病，并且可能对感染HIV的个体产生负面心理影响。
