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[一例伴有全葡萄膜炎的青少年类风湿关节炎]

[A case of juvenile rheumatoid arthritis with panuveitis].

作者信息

Ishihara M, Nakamura S, Okada K, Yokota S, Ohno S

机构信息

Department of Ophthalmology, Yokohama City University School of Medicine, Japan.

出版信息

Nippon Ganka Gakkai Zasshi. 1992 Jan;96(1):109-13.

PMID:1553868
Abstract

An association of bilateral panuveitis and juvenile rheumatoid arthritis (JRA) was recognized in a case which had an acute onset of systemic JRA without ocular manifestations 3 years previously. On the present occasion she had no active systemic inflammation at the onset of panuveitis. Fluorescein angiography demonstrated bilateral hypo-fluorescent patches at the posterior pole in the early stage and corresponding window defects in the late stage. Topical corticosteroid treatment and oral non-steroid therapy resulted in clinical improvement of the uveitis. It is concluded that ophthalmologic examinations, including fundus ophthalmoscopy, are important in patients with JRA, since there is a possibility of ocular symptoms, even in the systemic type in which ocular complications are rare, as well as in cases with a long interval since the onset of arthritis.

摘要

在一例患者中发现双侧全葡萄膜炎与青少年类风湿性关节炎(JRA)相关。该患者3年前急性起病的全身性JRA无眼部表现。此次全葡萄膜炎发作时,她无活动性全身炎症。荧光素血管造影显示早期后极部双侧低荧光斑,晚期出现相应的透见荧光缺损。局部糖皮质激素治疗和口服非甾体类药物治疗使葡萄膜炎临床症状改善。得出结论,对于JRA患者,包括眼底镜检查在内的眼科检查很重要,因为即使在眼部并发症罕见的全身型患者中,以及关节炎发病后间隔时间较长的病例中,也有可能出现眼部症状。

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