宽视野眼底荧光血管造影在儿童特发性关节炎相关性葡萄膜炎中的特征。
Widefield Fundus Fluorescein Angiography Features of Uveitis Associated with Juvenile Idiopathic Arthritis.
机构信息
Massachusetts Eye Research and Surgery Institution, Waltham, Massachusetts, USA.
The Ocular Immunology and Uveitis Foundation, Waltham, Massachusetts, USA.
出版信息
Ocul Immunol Inflamm. 2022 May 19;30(4):829-838. doi: 10.1080/09273948.2020.1834586. Epub 2020 Dec 2.
PURPOSE
To evaluate the wide-field fundus fluorescein angiography (WFA) characteristics of uveitis associated with juvenile idiopathic arthritis (JIA-uveitis).
METHODS
Retrospective review of records. WFA with Spectralis (Heidelberg) of JIA-uveitis patients were analyzed using the scoring system by Angiography Scoring for Uveitis Nomenclature.
RESULTS
Thirty-seven eyes of 20 patients were studied. A total score of at least 1 was noted in 27 eyes (72.97%). WFA features included optic disc hyperfluorescence (51.35%), macular leakage (27.03%), retinal vascular staining/leakage at posterior pole (27.03%) and peripheral retina (64.86%), capillary leakage at the posterior pole (37.84%), and peripheral retina (59.46%). A decision to change the management plan was made in 8 of 9 patients with bilateral quiet anterior chambers after WFA results.
CONCLUSION
More than 70% of JIA-uveitis eyes showed some WFA-evidence of posterior segment inflammation, which changed the course of therapy for a major proportion of patients with no clinically active anterior chamber inflammation.
目的
评估与幼年特发性关节炎（JIA-uveitis）相关的葡萄膜炎的宽视野眼底荧光素血管造影（WFA）特征。
方法
对 JIA-uveitis 患者的 Spectralis（海德堡）WFA 记录进行回顾性分析，使用葡萄膜炎命名法的血管造影评分系统进行分析。
结果
研究了 20 名患者的 37 只眼睛。27 只眼睛（72.97%）至少有 1 分的总评分。WFA 的特征包括视盘强荧光（51.35%）、黄斑渗漏（27.03%）、后极视网膜血管染色/渗漏（27.03%）和周边视网膜（64.86%）、后极（37.84%）和周边视网膜（59.46%）毛细血管渗漏。在 WFA 结果后，9 名双侧前房安静的患者中有 8 名决定改变治疗计划。
结论
超过 70%的 JIA-uveitis 眼出现了一些后段炎症的 WFA 证据，这改变了大部分没有临床活动性前房炎症的患者的治疗过程。
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