Terubayashi H, Tsutsumi M, Okamoto S, Ikebe H, Akagi Y
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1992 Jan;96(1):9-14.
In this study, we used ICR (Institute of Cancer Research) strain mouse because they showed hypergalactosemia but not cataractogenesis. We examined the proliferative ability of the lens epithelial cells by means of a whole-mount preparation of epithelium and 3H-thymidine autoradiography. An increased number of labelled cells was not found in the mouse. The increased proliferative ability of epithelial cells in rat galactose cataract did not seem to be caused by hypergalactosemia.
在本研究中，我们使用了癌症研究所（ICR）品系小鼠，因为它们表现出高半乳糖血症但未发生白内障。我们通过上皮细胞整装片和3H-胸腺嘧啶核苷放射自显影术检测晶状体上皮细胞的增殖能力。在小鼠中未发现标记细胞数量增加。大鼠半乳糖性白内障中上皮细胞增殖能力的增强似乎不是由高半乳糖血症引起的。
