Chen J, McCallum R W
University of Virginia Health Science Center, Charlottesville.
Am J Gastroenterol. 1992 Apr;87(4):477-82.
The aim of this study was to determine whether cutaneous electrogastrograms (EGGs) could be used to differentiate gastroparetic patients from asymptomatic healthy controls. Pre- and postprandial cutaneous EGGs were obtained from 24 asymptomatic healthy volunteers and 27 patients with gastroparesis documented by a delayed gastric emptying of a solid test meal. A definition of slow wave abnormality was introduced. For the fasted condition, all 24 controls showed highly regular, predominant peaks in the 2-4 cycles/min (cpm) range, in contrast to the patient group in which 11 subjects showed an absence of normal slow wave activity (p less than 0.001). For the postprandial condition, again, all 24 controls showed slow wave normality consisting of increased amplitude and regularity of the 2-4 cpm frequency component. This was in sharp contrast to the patient group in which 13 subjects showed abnormalities (p less than 0.0001). Approximately 75% of the patients had an abnormal pre- or postprandial EGG: four patients had abnormal EGGs both during fasting and after eating, seven patients had abnormal EGGs during fasting but normal EGGs after eating, and nine patients had normal EGGs during fasting but abnormal EGGs after eating. We conclude that the cutaneous EGG may be used to differentiate gastroparetic patients from asymptomatic normals.
本研究的目的是确定皮肤胃电图（EGG）是否可用于区分胃轻瘫患者和无症状健康对照者。从24名无症状健康志愿者和27名经固体试验餐胃排空延迟证实患有胃轻瘫的患者中获取餐前和餐后皮肤胃电图。引入了慢波异常的定义。在禁食状态下，所有24名对照者均显示出高度规则的、主要峰值在2 - 4次/分钟（cpm）范围内，相比之下，患者组中有11名受试者显示出正常慢波活动缺失（p小于0.001）。在餐后状态下，同样，所有24名对照者均显示慢波正常，包括2 - 4 cpm频率成分的振幅增加和规则性增强。这与患者组形成鲜明对比，患者组中有13名受试者显示异常（p小于0.0001）。大约75%的患者在餐前或餐后胃电图异常：4名患者在禁食和进食后胃电图均异常，7名患者禁食时胃电图异常但进食后正常，9名患者禁食时胃电图正常但进食后异常。我们得出结论，皮肤胃电图可用于区分胃轻瘫患者和无症状正常者。
