Lee Christopher S, Low Alexander H, Ender Peter T, Bodenheimer Henry C
Division of Digestive Diseases, Beth Israel Medical Center, New York, NY, USA.
Mt Sinai J Med. 2004 Oct;71(5):347-50.
Most cases of cytomegalovirus colitis occur in adults with severe immune deficiency. Only a few cases involving immunocompetent patients have been reported. We describe the first case reported in English, of cytomegalovirus colitis in an immunocompetent patient with preceding amebiasis. Eight previous cases have been reported of cytomegalovirus colitis occurring after colonic mucosal injury in immunocompetent patients. Similar to our case, all eight of these cases resolved without the use of antiviral therapy. This suggests that disruption of colonic mucosa may predispose immunocompetent patients to cytomegalovirus colitis, and that the colitis may become self-limited once the preceding intestinal damage resolves.
大多数巨细胞病毒性结肠炎病例发生在有严重免疫缺陷的成年人中。仅有少数涉及免疫功能正常患者的病例被报道。我们描述了首例英文报道的、在患有先前阿米巴病的免疫功能正常患者中发生的巨细胞病毒性结肠炎病例。此前已有8例关于免疫功能正常患者结肠黏膜损伤后发生巨细胞病毒性结肠炎的病例报道。与我们的病例相似,这8例病例均未使用抗病毒治疗即痊愈。这表明结肠黏膜的破坏可能使免疫功能正常的患者易患巨细胞病毒性结肠炎,并且一旦先前的肠道损伤痊愈,结肠炎可能会自行缓解。