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巨细胞病毒肠炎致老年免疫功能正常个体回肠穿孔

Cytomegalovirus enteritis causing ileal perforation in an elderly immunocompetent individual.

机构信息

Department of Internal Medicine, East-West Neo Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.

出版信息

Yonsei Med J. 2010 Mar;51(2):279-83. doi: 10.3349/ymj.2010.51.2.279. Epub 2010 Feb 12.

Abstract

Cytomegalovirus (CMV) infection is usually subclinical in immunocompetent individuals, however it can be life threatening in an elderly immunocompetent individual. We report a case of CMV enteritis causing ileal perforation in a physically active elderly man. An 88-year-old healthy man presented with abdominal pain and diarrhea. After initial conservative treatment, emergency laparotomy was performed for ileal perforation. The diagnosis of CMV enteritis was based on histological findings revealing many large cells with CMV inclusion bodies in the surgical specimen. In elderly individuals, even though they are immunocompetent, CMV enteritis may result in major complications such as bowel perforation, and it should be included in the differential diagnosis of diarrhea if it is resistant to conventional treatment.

摘要

巨细胞病毒(CMV)感染在免疫功能正常的个体中通常为无症状,但在免疫功能正常的老年个体中可能有生命危险。我们报告了一例巨细胞病毒肠炎导致活动能力强的老年男性回肠穿孔的病例。一位 88 岁健康男性因腹痛和腹泻就诊。初始保守治疗后,因回肠穿孔而行急诊剖腹手术。巨细胞病毒肠炎的诊断基于组织学发现,手术标本中可见许多含有巨细胞包涵体的大细胞。在老年个体中,即使他们免疫功能正常,巨细胞病毒肠炎也可能导致严重并发症,如肠穿孔,如果对常规治疗无效,应将其纳入腹泻的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c69/2824877/a7e2fe704d74/ymj-51-279-g001.jpg

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