来自松节油诱导的小鼠胸膜炎的中性粒细胞的精细结构，模拟类风湿关节炎细胞。

Fine structure of neutrophils from turpentine-induced pleuritis in mice, simulating rheumatoid arthritis cells.

作者信息

Nielsen M H, Faurschou P, Faarup P

机构信息

Institute of Pathological Anatomy, Copenhagen University, Denmark.

出版信息

APMIS. 1992 Feb;100(2):188-90. doi: 10.1111/j.1699-0463.1992.tb00860.x.

DOI:10.1111/j.1699-0463.1992.tb00860.x

PMID:1554495

Abstract

Pleural effusions were made by intrapleural turpentine installation in mice. The fine structure of inflammatory cells from the effusions was normal except for lipid inclusions. The same type of inclusion was previously found in neutrophils from pleural effusions in patients with tuberculous infection, rheumatoid disease, or carcinomatosis. The lipid inclusions observed in neutrophils from an irritative turpentine-induced pleurisy should be considered as "fatty change", and are structurally similar to the rheumatoid arthritis cells seen in patients with different diseases.

摘要

通过向小鼠胸腔内注入松节油来制造胸腔积液。除了脂质包涵体外，胸腔积液中炎症细胞的精细结构正常。此前在患有结核感染、类风湿性疾病或癌病的患者胸腔积液中的中性粒细胞中也发现了相同类型的包涵体。在刺激性松节油诱导的胸膜炎患者的中性粒细胞中观察到的脂质包涵体应被视为“脂肪变性”，并且在结构上与不同疾病患者中所见的类风湿关节炎细胞相似。