Brinkane A, Ounadi-Corbille W, Bellamy J, Leroy-Terquem E
Service de Médecine Interne, Centre Hospitalier Intercommunal de Meulan - Les Mureaux, Meulan.
Rev Pneumol Clin. 2004 Sep;60(4):239-41. doi: 10.1016/s0761-8417(04)72107-0.
Graves' disease is rarely associated with hypertrophy of the thymus which takes on a pseudotumor aspect. We observed a case in a 40-year-old woman who presented clinical and biological hyperthyroidism with anti-TSH receptor antibodies, favoring the diagnosis of Graves' disease which was confirmed by scintigraphy. The chest x-ray performed because of chest pain revealed enlargement of the mediastinum. The thoracic CT-scan without contrast injected showed a pseudotumor aspect of the thymus. Medical treatment with anti-thyroid drugs and beta blockers led to regression of the thymus mass. Knowledge of this type of association can avoid unnecessary thymus surgery. The clinical course is favorable irrespective of the type of anti-thyroid drug given.
格雷夫斯病很少与呈现假瘤样外观的胸腺肥大相关。我们观察了一例40岁女性病例,该患者有临床及生物学方面的甲状腺功能亢进,伴有抗促甲状腺激素受体抗体,支持格雷夫斯病的诊断,闪烁扫描术证实了这一诊断。因胸痛进行的胸部X光检查显示纵隔增宽。未注射造影剂的胸部CT扫描显示胸腺呈假瘤样外观。使用抗甲状腺药物和β受体阻滞剂进行药物治疗使胸腺肿块消退。了解这种关联类型可避免不必要的胸腺手术。无论使用何种抗甲状腺药物,临床病程均良好。