干细胞：科学、政策与伦理。
Stem cells: science, policy, and ethics.
作者信息
Fischbach Gerald D, Fischbach Ruth L
机构信息
Faculty of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
出版信息
J Clin Invest. 2004 Nov;114(10):1364-70. doi: 10.1172/JCI23549.
Abstract
Human embryonic stem cells offer the promise of a new regenerative medicine in which damaged adult cells can be replaced with new cells. Research is needed to determine the most viable stem cell lines and reliable ways to promote the differentiation of pluripotent stem cells into specific cell types (neurons, muscle cells, etc). To create new cell lines, it is necessary to destroy preimplantation blastocysts. This has led to an intense debate that threatens to limit embryonic stem cell research. The profound ethical issues raised call for informed, dispassionate debate.
摘要
人类胚胎干细胞为新型再生医学带来了希望，在这种医学中受损的成体细胞可被新细胞替代。需要开展研究以确定最具活力的干细胞系，以及促进多能干细胞分化为特定细胞类型（神经元、肌肉细胞等）的可靠方法。要创建新的细胞系，就有必要破坏植入前的囊胚。这引发了一场激烈的辩论，有可能限制胚胎干细胞研究。所引发的深刻伦理问题需要进行明智、冷静的辩论。
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