Dhar Pawan K, Meng Tan Chee, Somani Sandeep, Ye Li, Sakharkar Kishore, Krishnan Arun, Ridwan Azmi B M, Wah Sebastian Ho Kok, Chitre Mandar, Hao Zhu
Systems Biology Group, Bioinformatics Institute, 30 Biopolis Street, #07-01, Matrix, Singapore 138671.
Bioinformatics. 2005 Apr 1;21(7):1284-7. doi: 10.1093/bioinformatics/bti143. Epub 2004 Nov 16.
Modelling and simulation of complex cellular transactions involve development of platforms that understand diverse mathematical representations and are capable of handling large backend computations. Grid Cellware, an integrated modelling and simulation tool, has been developed to precisely address these niche requirements of the modelling community. Grid Cellware implements various pathway simulation algorithms along with adaptive Swarm algorithm for parameter estimation. For enchanced computational productivity Grid Cellware uses grid technology with Globus as the middleware.
复杂细胞活动的建模与模拟需要开发能够理解多种数学表示形式并能处理大量后端计算的平台。Grid Cellware是一款集成的建模与模拟工具,专为精确满足建模界的这些特殊需求而开发。Grid Cellware实现了各种通路模拟算法以及用于参数估计的自适应群体算法。为提高计算效率,Grid Cellware使用以Globus作为中间件的网格技术。